General information | Expression | lncRNA | Regulation | Mutation | Homolog | Interaction |
Basic Information |
|
---|---|
Gene ID | 5728 |
Name | PTEN |
Synonymous | phosphatase and tensin homolog;PTEN;phosphatase and tensin homolog |
Definition | MMAC1 phosphatase and tensin homolog deleted on chromosome 10|mitochondrial PTENalpha|mitochondrial phosphatase and tensin protein alpha|mutated in multiple advanced cancers 1|phosphatase and tensin-like protein|phosphatidylinositol 3,4,5-trisphosphate 3- |
Position | 10q23.3 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
in same component |
PDGFB | NCI_NATURE; |
in same component |
PDGFRB | NCI_NATURE; |
interacts with |
AKT1 | HPRD; |
interacts with |
ANAPC4 | INTACT; |
interacts with |
ANAPC5 | INTACT; |
interacts with |
ANAPC7 | INTACT; |
interacts with |
ANG | BIOGRID; |
interacts with |
ANG | HPRD; |
interacts with |
AR | BIOGRID; |
interacts with |
AR | CELL_MAP; |
interacts with |
AR | HPRD; |
interacts with |
CAV1 | BIOGRID; |
interacts with |
CAV1 | HPRD; |
interacts with |
CAV1 | MINT; |
interacts with |
CDC27 | INTACT; |
interacts with |
CHGB | BIOGRID; |
interacts with |
CHGB | HPRD; |
interacts with |
CHGB | MINT; |
interacts with |
COPS6 | BIOGRID; |
interacts with |
COPS6 | HPRD; |
interacts with |
COPS6 | MINT; |
interacts with |
CSNK2A1 | BIOGRID; |
interacts with |
CSNK2A1 | HPRD; |
interacts with |
CSNK2A2 | BIOGRID; |
interacts with |
CSNK2A2 | HPRD; |
interacts with |
DLG1 | HPRD; |
interacts with |
ESR1 | BIOGRID; |
interacts with |
HBA1 | BIOGRID; |
interacts with |
HBA1 | HPRD; |
interacts with |
HBA1 | MINT; |
interacts with |
MAGI2 | HPRD; |
interacts with |
MAGI3 | BIOGRID; |
interacts with |
MAGI3 | HPRD; |
interacts with |
MAGI3 | MINT; |
interacts with |
MAST1 | HPRD; |
interacts with |
MAST2 | HPRD; |
interacts with |
MAST3 | HPRD; |
interacts with |
MVP | BIOGRID; |
interacts with |
MVP | HPRD; |
interacts with |
NEDD4 | BIOGRID; |
interacts with |
PDGFRB | HPRD; |
interacts with |
PDGFRB | MINT; |
interacts with |
PPP1CA | HPRD; |
interacts with |
PRDX1 | MINT; |
interacts with |
PTK2 | BIOGRID; |
interacts with |
PXN | BIOGRID; |
interacts with |
PXN | HPRD; |
interacts with |
SLC9A3R1 | HPRD; |
interacts with |
SLC9A3R1 | MINT; |
interacts with |
SLC9A3R2 | HPRD; |
interacts with |
Slc9a3r2 | MINT; |
interacts with |
SLC9A3R2 | MINT; |
interacts with |
STK11 | HPRD; |
interacts with |
TP53 | BIOGRID; |
interacts with |
UBE2I | BIOGRID; |
interacts with |
UBE2I | HPRD; |
interacts with |
UBE2L3 | BIOGRID; |
interacts with |
UBE2L3 | HPRD; |
interacts with |
UTP14A | BIOGRID; |
interacts with |
UTP14A | HPRD; |
interacts with |
UTP14A | MINT; |
Metabolic Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
metabolic catalysis |
JUN | NCI_NATURE; |
metabolic catalysis |
TP53 | NCI_NATURE; |
sequential catalysis |
PTEN | HUMANCYC; |
Signaling Interaction [Top] | ||
Interaction Type |
Interactor |
Data Source |
---|---|---|
reacts with |
PDGFB | NCI_NATURE; |
reacts with |
PDGFRB | NCI_NATURE; |
reacts with |
PTEN | NCI_NATURE; |